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Kallikrein 6 Antibody (PA5-79568) in WB
Western blot analysis of Kallikrein 6/KLK6 in, Lane 1: human A431 whole cell lysates. Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. After Electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. The membrane was blocked with 5% non-fat milk/TBS for 1. 5 hour at RT. The membrane was incubated with Kallikrein 6 Polyclonal Antibody (Product # PA5-... View More
Product Details
PA5-79568
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived human Kallikrein 6 recombinant protein (Position: L22-K244).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2746683
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Kallikreins, including Kallikrein 6, are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: kallikrein 6; kallikrein 7; Kallikrein-6; Kallikrein6; MGC9355; Neurosin; Protease M; Serine protease 18; Serine protease 9; SP59; Zyme
Gene Aliases: Bssp; hK6; KLK6; Klk7; PRSS18; PRSS9; SP59
UniProt ID: (Human) Q6H301
Entrez Gene ID: (Human) 5653
central nervous system development
response to wounding
regulation of neuron projection development
protein processing
protein autoprocessing
collagen catabolic process
tissue regeneration
hormone metabolic process
myelination
amyloid precursor protein metabolic process
regulation of cell differentiation
positive regulation of G-protein coupled receptor protein signaling pathway
neuron death
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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