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Invitrogen
KappaB ras2 Polyclonal Antibody
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Product Details
PA5-20342
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 14 amino acid peptide from near the carboxy terminus of human KappaB ras2.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152313
Product Specific Information
A suggested positive control is RAW264.7 cell lysate.
PA5-20342 can be used with blocking peptide PEP-0462.
Target Information
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: I-kappa-B-interacting Ras-like protein 2; Kappa B-Ras protein 2; kappaB-Ras2; NF-kappa-B inhibitor-interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like 2; NFKB inhibitor interacting Ras-like protein 2
Gene Aliases: 2410003M04Rik; 4930527H08Rik; D630018G21Rik; kappaB-Ras2; KBRAS2; NKIRAS2
UniProt ID: (Human) Q9NYR9, (Mouse) Q9CR56
Entrez Gene ID: (Human) 28511, (Mouse) 71966, (Rat) 287707
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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