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NeoBiotechnologies
Ksp-Cadherin (Kidney-Specific Cadherin)/CDH16 Recombinant Rabbit Monoclonal Antibody (CDH16/9611R)
Product Details
1014-RBM16-P1
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
CDH16/9611R
Immunogen
Recombinant fragment (around aa350-550) of human CDH16 protein.
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control:Normal kidney or renal cell carcinoma.
Cellular Location: Cell Surface. Cytoplasm.
Target Information
The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-16, also known as Ksp-Cadherin, is a type I membrane protein which is kidney-specific. Cadherin-16 is expressed exclusively in the basolateral membrane of renal tubular epithelial cells. The human Ksp-cadherin gene (Cadherin-16) maps to chromosome 16q21-proximal 16q22. The mouse Ksp-cadherin gene was localized to a highly syntenic region of distal Chromosome 8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cadherin; cadherin 16, KSP-cadherin; Cadherin-16; Cadherin-16 (CDH16); CDH 16; Kidney-specific cadherin; KSP-cadherin; Ksp-cadherin antibody
Gene Aliases: CDH16; UNQ695/PRO1340
UniProt ID: (Human) O75309
Entrez Gene ID: (Human) 1014
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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