Product References
Lactate metabolism is essential in early-onset mitochondrial myopathy.
Science advances
Chen Z,Bordieanu B,Kesavan R,Lesner NP,Venigalla SSK,Shelton SD,DeBerardinis RJ,Mishra P
Wed Jan 04 00:00:00 EST 2023
mTOR inhibitor, gemcitabine and PD-L1 antibody blockade combination therapy suppresses pancreatic cancer progression via metabolic reprogramming and immune microenvironment remodeling in Trp53flox/+LSL-KrasG12D/+Pdx-1-Cre murine models.
Cancer letters
Qiu J,Feng M,Yang G,Cao Z,Liu Y,You L,Zhang T
Wed Feb 01 00:00:00 EST 2023
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.
Science advances
Jia M,Yue X,Sun W,Zhou Q,Chang C,Gong W,Feng J,Li X,Zhan R,Mo K,Zhang L,Qian Y,Sun Y,Wang A,Zou Y,Chen W,Li Y,Huang L,Yang Y,Zhao Y,Cheng X
Fri Jun 02 00:00:00 EDT 2023
The function of lactate dehydrogenase A in retinal neurons: implications to retinal degenerative diseases.
PNAS nexus
Rajala A,Bhat MA,Teel K,Gopinadhan Nair GK,Purcell L,Rajala RVS
Wed Mar 01 00:00:00 EST 2023
The function of lactate dehydrogenase A in retinal neurons: implications to retinal degenerative diseases.
PNAS nexus
Rajala A,Bhat MA,Teel K,Gopinadhan Nair GK,Purcell L,Rajala RVS
Wed Mar 01 00:00:00 EST 2023
Is Nrf2 Behind Endogenous Neuroprotection of the Hippocampal CA2-4,DG Region?
Molecular neurobiology
Lewczuk A,Zablocka B,Beresewicz-Haller M
Wed Mar 01 00:00:00 EST 2023
Effects of Fibroblast Growth Factor 21 on Lactate Uptake and Usage in Mice with Diabetes-Associated Cognitive Decline.
Molecular neurobiology
Zhao L,Jiang H,Xie J,Shen D,Yi Q,Yan J,Li C,Zheng H,Gao H
Thu Sep 01 00:00:00 EDT 2022
Effects of Fibroblast Growth Factor 21 on Lactate Uptake and Usage in Mice with Diabetes-Associated Cognitive Decline.
Molecular neurobiology
Zhao L,Jiang H,Xie J,Shen D,Yi Q,Yan J,Li C,Zheng H,Gao H
Thu Sep 01 00:00:00 EDT 2022
Effects of Fibroblast Growth Factor 21 on Lactate Uptake and Usage in Mice with Diabetes-Associated Cognitive Decline.
Molecular neurobiology
Zhao L,Jiang H,Xie J,Shen D,Yi Q,Yan J,Li C,Zheng H,Gao H
Thu Sep 01 00:00:00 EDT 2022
Effects of Fibroblast Growth Factor 21 on Lactate Uptake and Usage in Mice with Diabetes-Associated Cognitive Decline.
Molecular neurobiology
Zhao L,Jiang H,Xie J,Shen D,Yi Q,Yan J,Li C,Zheng H,Gao H
Thu Sep 01 00:00:00 EDT 2022
Changes in the Expression of MIF and Other Key Enzymes of Energy Metabolism in the Myocardia of Broiler Chickens with Ascites Syndrome.
Animals : an open access journal from MDPI
Li L,Jia Q,Chen L,Wang W
Tue Sep 20 00:00:00 EDT 2022
lncRNA HITT Inhibits Lactate Production by Repressing PKM2 Oligomerization to Reduce Tumor Growth and Macrophage Polarization.
Research (Washington, D.C.)
Zhao K,Wang X,Zhao D,Lin Q,Zhang Y,Hu Y
Tue Aug 02 00:00:00 EDT 2022
Genetic and Drug Inhibition of LDH-A: Effects on Murine Gliomas.
Cancers
Maeda M,Ko M,Mane MM,Cohen IJ,Shindo M,Vemuri K,Serganova I,Blasberg R
Fri May 06 00:00:00 EDT 2022
Comparative Proteomic Analysis of HPV(+) Oropharyngeal Squamous Cell Carcinoma Recurrence.
Journal of proteome research
Ho AS,Robinson A,Shon W,Laury A,Raedschelders K,Venkatraman V,Holewinski R,Zhang Y,Shiao SL,Chen MM,Mallen-St Clair J,Lin DC,Zumsteg ZS,Van Eyk JE
Fri Jan 07 00:00:00 EST 2022
Lactate Activates AMPK Remodeling of the Cellular Metabolic Profile and Promotes the Proliferation and Differentiation of C2C12 Myoblasts.
International journal of molecular sciences
Zhou Y,Liu X,Huang C,Lin D
Sun Nov 13 00:00:00 EST 2022
Lactate Dehydrogenase B Is Required for Pancreatic Cancer Cell Immortalization Through Activation of Telomerase Activity.
Frontiers in oncology
Wang R,Li J,Zhang C,Guan X,Qin B,Jin R,Qin L,Xu S,Zhang X,Liu R,Ye Q,Cheng L
Sat Jul 16 00:00:00 EDT 2022
Enhancement of anaerobic glycolysis - a role of PGC-1α4 in resistance exercise.
Nature communications
Koh JH,Pataky MW,Dasari S,Klaus KA,Vuckovic I,Ruegsegger GN,Kumar AP,Robinson MM,Nair KS
Thu Apr 28 00:00:00 EDT 2022
Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis.
Frontiers in pharmacology
Chen W,Zhang J,Zhong W,Liu Y,Lu Y,Zeng Z,Huang H,Wan X,Meng X,Zou F,Cai S,Dong H
Tue Oct 05 00:00:00 EDT 2021
Proteome analysis identified proteins associated with mitochondrial function and inflammation activation crucially regulating the pathogenesis of fatty liver disease.
BMC genomics
Zhang L,Liu T,Hu C,Zhang X,Zhang Q,Shi K
Sat Sep 04 00:00:00 EDT 2021
AMPKα loss promotes KRAS-mediated lung tumorigenesis.
Cell death and differentiation
La Montagna M,Shi L,Magee P,Sahoo S,Fassan M,Garofalo M
Wed Sep 01 00:00:00 EDT 2021
Metabolic remodelling during early mouse embryo development.
Nature metabolism
Zhao J,Yao K,Yu H,Zhang L,Xu Y,Chen L,Sun Z,Zhu Y,Zhang C,Qian Y,Ji S,Pan H,Zhang M,Chen J,Correia C,Weiskittel T,Lin DW,Zhao Y,Chandrasekaran S,Fu X,Zhang D,Fan HY,Xie W,Li H,Hu Z,Zhang J
Fri Oct 01 00:00:00 EDT 2021
Dysfunctional lactate metabolism in human alveolar type II cells from idiopathic pulmonary fibrosis lung explant tissue.
Respiratory research
Newton DA,Lottes RG,Ryan RM,Spyropoulos DD,Baatz JE
Thu Oct 28 00:00:00 EDT 2021
Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.
Nature communications
Wang C,Li Y,Yan S,Wang H,Shao X,Xiao M,Yang B,Qin G,Kong R,Chen R,Zhang N
Mon Jun 22 00:00:00 EDT 2020
Effects of glucose metabolism pathways on nuclear and cytoplasmic maturation of pig oocytes.
Scientific reports
Wen J,Wang GL,Yuan HJ,Zhang J,Xie HL,Gong S,Han X,Tan JH
Mon Feb 17 00:00:00 EST 2020
A glycolytic shift in Schwann cells supports injured axons.
Nature neuroscience
Babetto E,Wong KM,Beirowski B
Thu Oct 01 00:00:00 EDT 2020
ITGB2-mediated metabolic switch in CAFs promotes OSCC proliferation by oxidation of NADH in mitochondrial oxidative phosphorylation system.
Theranostics
Zhang X,Dong Y,Zhao M,Ding L,Yang X,Jing Y,Song Y,Chen S,Hu Q,Ni Y
Mon May 31 00:00:00 EDT 2021
ITGB2-mediated metabolic switch in CAFs promotes OSCC proliferation by oxidation of NADH in mitochondrial oxidative phosphorylation system.
Theranostics
Zhang X,Dong Y,Zhao M,Ding L,Yang X,Jing Y,Song Y,Chen S,Hu Q,Ni Y
Mon May 31 00:00:00 EDT 2021
LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis.
Nature communications
Arra M,Swarnkar G,Ke K,Otero JE,Ying J,Duan X,Maruyama T,Rai MF,O'Keefe RJ,Mbalaviele G,Shen J,Abu-Amer Y
Thu Jul 09 00:00:00 EDT 2020
Glutathione S-Transferase Mu-3 Predicts a Better Prognosis and Inhibits Malignant Behavior and Glycolysis in Pancreatic Cancer.
Frontiers in oncology
Wang S,Yang J,Ding C,Li J,You L,Dai M,Zhao Y
Thu Oct 01 00:00:00 EDT 2020
Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer.
Cancer research
Cao D,Qi Z,Pang Y,Li H,Xie H,Wu J,Huang Y,Zhu Y,Shen Y,Zhu Y,Dai B,Hu X,Ye D,Wang Z
Wed May 15 00:00:00 EDT 2019
Bufalin inhibits glycolysis-induced cell growth and proliferation through the suppression of Integrin β2/FAK signaling pathway in ovarian cancer.
American journal of cancer research
Li H,Hu S,Pang Y,Li M,Chen L,Liu F,Liu M,Wang Z,Cheng X
Fri Apr 08 00:00:00 EDT 2022
Bufalin inhibits glycolysis-induced cell growth and proliferation through the suppression of Integrin β2/FAK signaling pathway in ovarian cancer.
American journal of cancer research
Li H,Hu S,Pang Y,Li M,Chen L,Liu F,Liu M,Wang Z,Cheng X
Fri Apr 08 00:00:00 EDT 2022
LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer.
Journal of experimental & clinical cancer research : CR
Feng M,Xiong G,Cao Z,Yang G,Zheng S,Qiu J,You L,Zheng L,Zhang T,Zhao Y
Mon Nov 12 00:00:00 EST 2018
LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer.
Journal of experimental & clinical cancer research : CR
Feng M,Xiong G,Cao Z,Yang G,Zheng S,Qiu J,You L,Zheng L,Zhang T,Zhao Y
Mon Nov 12 00:00:00 EST 2018
LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer.
Journal of experimental & clinical cancer research : CR
Feng M,Xiong G,Cao Z,Yang G,Zheng S,Qiu J,You L,Zheng L,Zhang T,Zhao Y
Mon Nov 12 00:00:00 EST 2018
LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer.
Journal of experimental & clinical cancer research : CR
Feng M,Xiong G,Cao Z,Yang G,Zheng S,Qiu J,You L,Zheng L,Zhang T,Zhao Y
Mon Nov 12 00:00:00 EST 2018
The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway.
Stem cell reports
Sun Z,Zhu M,Lv P,Cheng L,Wang Q,Tian P,Yan Z,Wen B
Tue Sep 11 00:00:00 EDT 2018
The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway.
Stem cell reports
Sun Z,Zhu M,Lv P,Cheng L,Wang Q,Tian P,Yan Z,Wen B
Tue Sep 11 00:00:00 EDT 2018
The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer.
Journal of hematology & oncology
Jiang W,He T,Liu S,Zheng Y,Xiang L,Pei X,Wang Z,Yang H
Fri Dec 14 00:00:00 EST 2018
The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer.
Journal of hematology & oncology
Jiang W,He T,Liu S,Zheng Y,Xiang L,Pei X,Wang Z,Yang H
Fri Dec 14 00:00:00 EST 2018
The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer.
Journal of hematology & oncology
Jiang W,He T,Liu S,Zheng Y,Xiang L,Pei X,Wang Z,Yang H
Fri Dec 14 00:00:00 EST 2018
The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer.
Journal of hematology & oncology
Jiang W,He T,Liu S,Zheng Y,Xiang L,Pei X,Wang Z,Yang H
Fri Dec 14 00:00:00 EST 2018
A large-scale targeted proteomics assay resource based on an in vitro human proteome.
Nature methods
Matsumoto M,Matsuzaki F,Oshikawa K,Goshima N,Mori M,Kawamura Y,Ogawa K,Fukuda E,Nakatsumi H,Natsume T,Fukui K,Horimoto K,Nagashima T,Funayama R,Nakayama K,Nakayama KI
Wed Mar 01 00:00:00 EST 2017
A large-scale targeted proteomics assay resource based on an in vitro human proteome.
Nature methods
Matsumoto M,Matsuzaki F,Oshikawa K,Goshima N,Mori M,Kawamura Y,Ogawa K,Fukuda E,Nakatsumi H,Natsume T,Fukui K,Horimoto K,Nagashima T,Funayama R,Nakayama K,Nakayama KI
Wed Mar 01 00:00:00 EST 2017
miR-375 Regulates Invasion-Related Proteins Vimentin and L-Plastin.
The American journal of pathology
Jimenez L,Lim J,Burd B,Harris TM,Ow TJ,Kawachi N,Belbin TJ,Angeletti R,Prystowsky MB,Childs G,Segall JE
Sat Jul 01 00:00:00 EDT 2017
miR-375 Regulates Invasion-Related Proteins Vimentin and L-Plastin.
The American journal of pathology
Jimenez L,Lim J,Burd B,Harris TM,Ow TJ,Kawachi N,Belbin TJ,Angeletti R,Prystowsky MB,Childs G,Segall JE
Sat Jul 01 00:00:00 EDT 2017
Fructose‑1,6‑bisphosphatase‑1 decrease may promote carcinogenesis and chemoresistance in cervical cancer.
Molecular medicine reports
Li H,Li M,Pang Y,Liu F,Sheng D,Cheng X
Fri Dec 01 00:00:00 EST 2017
Fructose‑1,6‑bisphosphatase‑1 decrease may promote carcinogenesis and chemoresistance in cervical cancer.
Molecular medicine reports
Li H,Li M,Pang Y,Liu F,Sheng D,Cheng X
Fri Dec 01 00:00:00 EST 2017
Proteomic analysis indicates that mitochondrial energy metabolism in skeletal muscle tissue is negatively correlated with feed efficiency in pigs.
Scientific reports
Fu L,Xu Y,Hou Y,Qi X,Zhou L,Liu H,Luan Y,Jing L,Miao Y,Zhao S,Liu H,Li X
Mon Mar 27 00:00:00 EDT 2017
Proteomic analysis indicates that mitochondrial energy metabolism in skeletal muscle tissue is negatively correlated with feed efficiency in pigs.
Scientific reports
Fu L,Xu Y,Hou Y,Qi X,Zhou L,Liu H,Luan Y,Jing L,Miao Y,Zhao S,Liu H,Li X
Mon Mar 27 00:00:00 EDT 2017
Cisplatin suppresses the growth and proliferation of breast and cervical cancer cell lines by inhibiting integrin β5-mediated glycolysis.
American journal of cancer research
Wang S,Xie J,Li J,Liu F,Wu X,Wang Z
Mon Jun 13 00:00:00 EDT 2016
Cisplatin suppresses the growth and proliferation of breast and cervical cancer cell lines by inhibiting integrin β5-mediated glycolysis.
American journal of cancer research
Wang S,Xie J,Li J,Liu F,Wu X,Wang Z
Mon Jun 13 00:00:00 EDT 2016
Cisplatin suppresses the growth and proliferation of breast and cervical cancer cell lines by inhibiting integrin β5-mediated glycolysis.
American journal of cancer research
Wang S,Xie J,Li J,Liu F,Wu X,Wang Z
Mon Jun 13 00:00:00 EDT 2016
Cisplatin suppresses the growth and proliferation of breast and cervical cancer cell lines by inhibiting integrin β5-mediated glycolysis.
American journal of cancer research
Wang S,Xie J,Li J,Liu F,Wu X,Wang Z
Mon Jun 13 00:00:00 EDT 2016
Laser capture microdissection-directed profiling of glycolytic and mTOR pathways in areas of selectively ablated Müller cells in the murine retina.
Investigative ophthalmology & visual science
Chung SH,Shen W,Gillies MC
Wed Oct 09 00:00:00 EDT 2013
Laser capture microdissection-directed profiling of glycolytic and mTOR pathways in areas of selectively ablated Müller cells in the murine retina.
Investigative ophthalmology & visual science
Chung SH,Shen W,Gillies MC
Wed Oct 09 00:00:00 EDT 2013
Probing early tumor response to radiation therapy using hyperpolarized [1-¹³C]pyruvate in MDA-MB-231 xenografts.
PloS one
Chen AP,Chu W,Gu YP,Cunningham CH
Thu Aug 08 00:00:00 EDT 2013
Probing early tumor response to radiation therapy using hyperpolarized [1-¹³C]pyruvate in MDA-MB-231 xenografts.
PloS one
Chen AP,Chu W,Gu YP,Cunningham CH
Thu Aug 08 00:00:00 EDT 2013
Differential redox proteomics allows identification of proteins reversibly oxidized at cysteine residues in endothelial cells in response to acute hypoxia.
Journal of proteomics
Izquierdo-Álvarez A,Ramos E,Villanueva J,Hernansanz-Agustín P,Fernández-Rodríguez R,Tello D,Carrascal M,Martínez-Ruiz A
Tue Sep 18 00:00:00 EDT 2012
Differential redox proteomics allows identification of proteins reversibly oxidized at cysteine residues in endothelial cells in response to acute hypoxia.
Journal of proteomics
Izquierdo-Álvarez A,Ramos E,Villanueva J,Hernansanz-Agustín P,Fernández-Rodríguez R,Tello D,Carrascal M,Martínez-Ruiz A
Tue Sep 18 00:00:00 EDT 2012
Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
Proceedings of the National Academy of Sciences of the United States of America
Sun Q,Chen X,Ma J,Peng H,Wang F,Zha X,Wang Y,Jing Y,Yang H,Chen R,Chang L,Zhang Y,Goto J,Onda H,Chen T,Wang MR,Lu Y,You H,Kwiatkowski D,Zhang H
Tue Mar 08 00:00:00 EST 2011
Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
Proceedings of the National Academy of Sciences of the United States of America
Sun Q,Chen X,Ma J,Peng H,Wang F,Zha X,Wang Y,Jing Y,Yang H,Chen R,Chang L,Zhang Y,Goto J,Onda H,Chen T,Wang MR,Lu Y,You H,Kwiatkowski D,Zhang H
Tue Mar 08 00:00:00 EST 2011
