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Immunogen sequence: LEEMAYSAYVP QDGTMLTALH SYMDAHSPTT LGLQPLLPHS MTQLPISHT
Highest antigen sequence identity to the following orthologs - mouse 92%, rat 54%.
Members of the LIM homeobox gene family, such as LHX8, encode transcription regulators that share common structural features. They all contain 2 tandemly repeated cysteine-rich double-zinc finger motifs, called LIM domains, in addition to a homeodomain. The homeodomain is a DNA-binding domain, and the LIM domains are essential for regulating the activity of these molecules by interacting with other proteins. Members of the LIM homeobox gene family are required for the patterning or the specification and differentiation of different cell types during embryonic development (Zhao et al., 1999 [PubMed 10611327]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LIM homeobox protein 8; LIM Homeodomain 8; LIM-homeodomain protein Lhx8; LIM/homeobox protein Lhx8
Gene Aliases: LHX7; LHX8
UniProt ID: (Human) Q68G74
Entrez Gene ID: (Human) 431707
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