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This antibody recognizes all the isoforms of LPHN3 and has no cross reaction with LPHN1 and LPHN2.
Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adhesion G protein-coupled receptor L3; Calcium-independent alpha-latrotoxin receptor 3; calcium-independent alpha-latrotoxin receptor homolog 3; CIRL-3; latrophilin 3; latrophilin homolog 3 (cow); Latrophilin-3; lectomedin 3; Lectomedin-3; Lph3
Gene Aliases: 5430402I23Rik; ADGRL3; CIRL-3; CIRL3; CL3; D130075K09Rik; Gm1379; KIAA0768; LEC3; LPHN3; mKIAA0768
UniProt ID: (Human) Q9HAR2, (Mouse) Q80TS3, (Rat) Q9Z173
Entrez Gene ID: (Human) 23284, (Mouse) 319387, (Rat) 170641
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