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LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha lipase; Lipoprotein lipase; LPL; O 1-4-5; Phospholipase A1
Gene Aliases: HDLCQ11; LIPD; LPL
UniProt ID: (Human) P06858, (Rat) Q06000, (Mouse) P11152
Entrez Gene ID: (Human) 4023, (Rat) 24539, (Mouse) 16956
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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