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The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat
Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8A constitutes a pore-forming subunit or whether it is closely associated with the pore and mediates channel properties such as ion selectivity. Involved in B-cell development: required for the pro-B cell to pre-B cell transition. Also required for T-cell development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ebo; HsLRRC8A; leucine rich repeat containing 8 family, member A; leucine-rich repeat containing 8 family member A; leucine-rich repeat-containing 8; Leucine-rich repeat-containing protein 8A; Protein ebouriffe; Swelling protein 1; Volume-regulated anion channel subunit LRRC8A
Gene Aliases: AGM5; KIAA1437; LRRC8; LRRC8A; mKIAA1437; SWELL1; UNQ221/PRO247
UniProt ID: (Human) Q8IWT6, (Mouse) Q80WG5
Entrez Gene ID: (Human) 56262, (Mouse) 241296
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