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Invitrogen
LRRN1 Polyclonal Antibody
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Product Details
PA5-52786
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LRRN1. Recombinant protein control fragment (Product #RP-90482).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2643565
Product Specific Information
Immunogen sequence: NSNKTNIRFM EPLSMFCAMP PEYKGHQVKE VLIQDSSEQC LPMISHDSFP NRLNVDIGTT VFLDCRAMAE PEPEIYWVTP IGNKITVETL SDKYKLSSEG TLEISNIQIE DSGRYTCVAQ NVQGAD
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
Target Information
Leucine-rich repeat neuronal 1 (LRRN1) is a gene located on chromosome 3q23, which encodes a transmembrane protein belonging to the leucine-rich repeat (LRR) family. This protein plays a significant role in neural development and synaptic plasticity due to its involvement in cell-cell adhesion and signaling pathways. LRRN1 has been implicated in brain development processes, especially in synapse organization and neuronal differentiation. Its expression is primarily localized to the central nervous system, indicating its importance in neurodevelopmental functions. Research has highlighted LRRN1's potential involvement in cognitive functions, and alterations in its expression have been associated with various neurological disorders. Additionally, LRRN1 is thought to contribute to the establishment of neuronal networks by modulating interactions between neurons through extracellular matrix components. Current studies are exploring its contributions to neuropathological conditions, providing insights into its relevance in brain health and disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: fibronectin type III, immunoglobulin and leucine rich repeat domains 3; Leucine-rich repeat neuronal protein 1; LRN; Neuronal leucine-rich repeat protein 1; NLRR-1
Gene Aliases: FIGLER3; KIAA1497; LRRN1; Nbla10449; NLRR-1; UNQ693/PRO1338
UniProt ID: (Human) Q6UXK5
Entrez Gene ID: (Human) 57633
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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