Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
A suggested positive control is Hela cell lysate.
PA5-21101 can be used with blocking peptide PEP-1215.
The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Little is known about the function of LRRTM4; in mouse, it is expressed in the limb mesenchyme, neural tube, caudal mesoderm and in three distinct regions of the head. Later expression occurs in a subset of the developing sclerotome. Its similarity to other LRRTM family members suggests that LRRTM4 may also play a role in the development and maintenance of the vertebrate nervous system.
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Protein Aliases: FLJ12568; leucine-rich repeat transmembrane neuronal 4 protein; Leucine-rich repeat transmembrane neuronal protein 4; MGC120633; MGC120636
Gene Aliases: LRRTM4; UNQ3075/PRO9907
UniProt ID: (Human) Q86VH4
Entrez Gene ID: (Human) 80059
Molecular Function:
transmembrane signal receptor
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