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Application
FIGURE: 1 / 2
LSM1 Antibody (PA5-87186) in ICC/IF
Immunocytochemistry analysis of LSM1 in L929 cells. Samples were incubated with LSM1 polyclonal antibody (Product # PA5-87186) using a dilution of 1:100. Blue: DAPI for nuclear staining.
Product Details
PA5-87186
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein of human LSM1.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2803936
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cancer-associated Sm protein; Cancer-associated Sm-like; cancer-associated Sm-like protein; cancer‐associated Sm protein; LSM1 homolog, U6 small nuclear RNA associated; LSM1 mRNA degradation associated; LSM1, U6 small nuclear RNA associated; LSM1-like protein U6 small nuclear RNA associated; Small nuclear ribonuclear CaSm; U6 snRNA-associated Sm-like protein LSm1
Gene Aliases: 2810025O06Rik; CASM; LSM1; YJL124C
UniProt ID: (Human) O15116, (Mouse) Q8VC85
Entrez Gene ID: (Human) 27257, (Mouse) 67207
deadenylation-dependent decapping of nuclear-transcribed mRNA
RNA splicing, via transesterification reactions
mRNA processing
RNA splicing
stem cell population maintenance
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
negative regulation of neuron differentiation
histone mRNA catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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