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Proteintech
LYPD3 Recombinant Rabbit Monoclonal Antibody (240347C5)
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Product Details
83345-1-RR
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
240347C5
Immunogen
LYPD3 fusion protein Ag34961
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: LECYSCVQKA DDGCSPNKMK TVKCAPGVDV CTEAVGAVET IHGQFSLAVR GCGSGLPGKN DRGLDLHGLL AFIQLQQCAQ DRCNAKLNLT SRALDPAGNE SAYPPNGVEC YSCVGLSREA CQGTSPPVVS CYNASDHVYK GCFDGNVTLT AANVTVSLPV RGCVQDEFCT RDGVTGPGFT LSGSCCQGSR CNSDLRNKTY FSPRIPPLVR LPPPEPTTVA STTSVTTSTS APVRPTSTTK PMPAPTSQTP RQGVEHEASR DEEPRLTGGA AGHQDRSNSG QYPAKGGPQQ PHNKGC
Target Information
Lymphocyte antigen 6 family member D3 (LYPD3), also known as C4.4A, is a gene located on chromosome 19q13.11 that encodes a glycosylphosphatidylinositol (GPI)-anchored protein belonging to the Ly6/uPAR superfamily. LYPD3 is expressed in various epithelial tissues and is implicated in cellular adhesion and migration processes. The protein plays a significant role in tumor progression and metastasis, with its expression being notably upregulated in several cancers, including squamous cell carcinoma and lung cancer. LYPD3 contributes to the invasive behavior of cancer cells by interacting with matrix components and modulating signaling pathways related to cell motility and adhesion. Its involvement in cancer biology makes LYPD3 a potential biomarker for tumor aggressiveness and a target for therapeutic intervention aimed at inhibiting cancer cell dissemination. Research continues to explore its functional mechanisms in oncogenesis and potential applications in cancer treatment strategies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2310061G07Rik; GPI-anchored metastasis-associated protein C4.4A homolog; GPI-anchored metastasis-associated protein homolog; Ly6/PLAUR domain-containing protein 3; Matrigel-induced gene C4 protein; MIG-C4
Gene Aliases: C4.4A; LYPD3; UNQ491/PRO1007
UniProt ID: (Human) O95274
Entrez Gene ID: (Human) 27076
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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