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Ly49 receptors (Lectin like receptor) exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells.
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Protein Aliases: Killer cell lectin-like receptor 6; Ly-49; Ly-49f; Lymphocyte antigen 49f; T-cell surface glycoprotein Ly-49F
Gene Aliases: Klra6; Ly-49f; Ly49-f; Ly49F
UniProt ID: (Mouse) Q60653
Entrez Gene ID: (Mouse) 16637
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