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FIGURE: 1 / 1
MAT1A Antibody (PA5-117063) in WB
Western blot analysis of MAT1A in extracts of various cell lines. Samples were incubated with MAT1A Polyclonal antibody (Product # PA5-117063) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-117063
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-395 of human MAT1A (NP_0004201)
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901693
Product Specific Information
Positive Samples: HepG2, 293T, Mouse liver, Rat liver
Immunogen sequence: MNGPVDGLCD HSLSEGVFMF TSESVGEGHP DKICDQISDA VLDAHLKQDP NAKVACETVC KTGMVLLCGE ITSMAMVDYQ RVVRDTIKHI GYDDSAKGFD FKTCNVLVAL EQQSPDIAQC VHLDRNEEDV GAGDQGLMFG YATDETEECM PLTIILAHKL NARMADLRRS GLLPWLRPDS KTQVTVQYMQ DNGAVIPVRI HTIVISVQHN EDITLEEMRR ALKEQVIRAV VPAKYLDEDT VYHLQPSGRF VIGGPQGDAG VTGRKIIVDT YGGWGAHGGG AFSGKDYTKV DRSAAYAARW VAKSLVKAGL CRRVLVQVSY AIGVAEPLSI SIFTYGTSQK TERELLDVVH KNFDLRPGVI VRDLDLKKPI YQKTACYGHF GRSEFPWEVP RKLVF
Target Information
MAT1A catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AdoMet synthase 1; adoMet synthetase 1; MAT 1; MAT-I/III; Methionine adenosyltransferase 1; methionine adenosyltransferase I, alpha; Methionine adenosyltransferase I/III; S - adenosylmethionine synthetase; S-adenosylmethionine synthase isoform type-1; S-adenosylmethionine synthetase isoform type-1
Gene Aliases: AdoMet; AI046368; Ams; AMS1; MAT; MAT1A; MATA1; SADE; SAMS; SAMS1; SAS
UniProt ID: (Human) Q00266, (Rat) P13444, (Mouse) Q91X83
Entrez Gene ID: (Human) 4143, (Rat) 25331, (Mouse) 11720
methionine adenosyltransferase activity
ATP binding
metal ion binding
selenomethionine adenosyltransferase activity
magnesium ion binding
amino acid binding
identical protein binding
protein homodimerization activity
ADP binding
protein dimerization activity
nucleotide binding
transferase activity
nucleotidyltransferase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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