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Application
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MBD3 Antibody (53615-MSM1-P1ABX) in Flow
Flow Cytometry analysis of PFA-fixed HeLa cells using MBD3 Monoclonal Antibody (Product # 53615-MSM1-P1ABX) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).
Product Details
53615-MSM1-P1ABX
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
PCRP-MBD3-1C4
Immunogen
Recombinant full-length human MBD3 protein
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Regulator of genomic integrity and cellular response to DNA damage acting through ATR-mediated checkpoint signaling. Necessary for centrosome duplication. It functions as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, two molecules involved in centriole formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CpG binding domain 3; Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3
Gene Aliases: MBD3
UniProt ID: (Human) O95983
Entrez Gene ID: (Human) 53615
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
methylation-dependent chromatin silencing
transcription, DNA-templated
brain development
heart development
aging
tissue development
histone acetylation
histone deacetylation
response to nutrient levels
response to estradiol
ATP-dependent chromatin remodeling
regulation of DNA methylation
embryonic organ development
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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