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Alomone Labs, LTD
MC2 Receptor (extracellular) Polyclonal Antibody
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Application
FIGURE: 1 / 2
MC2 Receptor (extracellular) Antibody (AMR-022-200UL) in IHC (P)
Expression of MC2R in rat adrenal gland - Immunohistochemical staining of paraffin embeddedrat adrenal cortex section using Anti-MC2 Receptor (extracellular) Antibody (#AMR-022), (1:100).Shown arethe capsule (C), thezona glomerulosa (ZG) and thezona fasciculata (ZF) of the adrenal cortex. Note that the staining (brown) is specific for cells of the adrenal gland while no staining is present in the dense conn... View More
Product Details
AMR-022-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)RNMGYLKPRGSFE,corresponding to amino acid residues 87-99 of human MC2R, 1st extracellular loop
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins are peptides derived from pro-opiomelanocortin. MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACTH receptor; Adrenocorticotropic hormone receptor; Adrenocorticotropin receptor; corticotropin receptor; MC2 receptor; MC2-R; melanocortin 2 receptor (adrenocorticotropic hormone); Melanocortin receptor 2; MGC125798
Gene Aliases: ACTH-R; ACTHR; MC2-R; MC2R
UniProt ID: (Human) Q01718, (Mouse) Q64326
Entrez Gene ID: (Human) 4158, (Mouse) 17200, (Rat) 282839
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