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Product Details
PA5-59489
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MCAF2. Recombinant protein control fragment (Product #RP-98718).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2643799
Product Specific Information
Immunogen sequence: RNKHEGIADK LLAKIAKLQR RIKTVLLFQR NCLKPNMLSS NGASKVANSE AMILDKNLES VNSPIEKSSV NYEPSNPSEK GSKKINLSSD QNKSVSESNN DD
Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 52%.
Target Information
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating transcription factor 7-interacting protein 2; ATF7-interacting protein 2; MBD1-containing chromatin associated factor 2; MBD1-containing chromatin-associated factor 2
Gene Aliases: ATF7IP2; MCAF2
UniProt ID: (Human) Q5U623
Entrez Gene ID: (Human) 80063
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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