Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
15196-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MED10 Fusion Protein Ag7336 (1-135 aa encoded by BC003353)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAEKFDHLE EHLEKFVENI RQLGIIVSDF QPSSQAGLNQ KLNFIVTGLQ DIDKCRQQLH DITVPLEVFE YIDQGRNPQL YTKECLERAL AKNEQVKGKI DTMKKFKSLL IQELSKVFPE DMAKYRSIRG EDHPPS (1-135 aa encoded by B C003353)
Target Information
MED10 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Mediator complex subunit 10; Mediator of RNA polymerase II transcription subunit 10; mediator of RNA polymerase II transcription, subunit 10; mediator of RNA polymerase II transcription, subunit 10 homolog (NUT2, S. cerevisiae); Transformation-related gene 17 protein; Transformation-related gene 20 protein; TRG-17; TRG-20
Gene Aliases: AA959813; AI385605; C78613; D13Wsu50e; L6; MED10; NUT2; RGD1310128; TRG17; TRG20
UniProt ID: (Human) Q9BTT4, (Mouse) Q9CXU0
Entrez Gene ID: (Human) 84246, (Rat) 290939, (Mouse) 28077
transcription initiation from RNA polymerase II promoter
protein ubiquitination
stem cell population maintenance
positive regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support