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Search Thermo Fisher Scientific
Sequence of this protein is as follows: SRPSPFRPAA PKAGPPGLVH PLFSPSHLTS KTPPPLYLPT EGRRSDLPGG LAGPRGGLNT SRSLYSGLQN P
The myocyte enhancer factor-2 (MEF-2) family of transcription factors associated with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LOC729991-MEF2B; MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B); MEF2BNB-MEF2B; Myocyte-specific enhancer factor 2B; RSRFR2; Serum response factor-like protein 2
Gene Aliases: MEF2B; RSRFR2; XMEF2
UniProt ID: (Human) Q02080
Entrez Gene ID: (Human) 100271849
Molecular Function:
MADS box transcription factor
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