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MEIS1 Antibody (TA809623) in IHC (P)
Immunohistochemical staining of paraffin-embedded human bladder tissue within the normal limits using anti-MEIS1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA809623)(1:500).
Product Details
TA809623
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI3H2
Immunogen
Human recombinant protein fragment corresponding to amino acids 176-390 of human MEIS1 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE family of homeodomain-containing proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Homeobox protein Meis1; leukemogenic homolog protein; Meis1, myeloid ecotropic viral integration site 1 homolog; MGC43380; WUGSC:H_NH0444B04.1
Gene Aliases: MEIS1
UniProt ID: (Human) O00470
Entrez Gene ID: (Human) 4211
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
protein heterodimerization activity
homeodomain transcription factor
angiogenesis
lens morphogenesis in camera-type eye
transcription from RNA polymerase II promoter
locomotory behavior
megakaryocyte development
negative regulation of myeloid cell differentiation
negative regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
definitive hemopoiesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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