Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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Immunogen sequence: LKNNSIPDKQ ITASSSYKTW GLHLFSWNPS YARLDKQGNF NAWVAGSYGN DQWLQVDLGS SKEVTGIITQ GARNFGSVQF VASYKVAYSN DSANWTEYQD PRTGSSKIFP GNWDNHSHKK NLFETPILAR YVRILPVAWH NRIALRLEL
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
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