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Immunogen sequence: SSYEELKEI SVVVHLADFN SSWRDAMVQD ITQKFAHHII AGRLMVIHAP EEYYPILDGL KRNYNDPEDR VKFRSKQNVD YAFLLNFCAN TSDYYVMLED DVRCSKNFLT AIKKVIASLE GTYWVTLEFS KLGYIGKLYH SHDLPRLAHF LLMFYQEMPC DWLLTHFRGL LAQKNVIRFK PSLFQHMGYY SSYKGTENKL KDDDFEEESF DIPDNPPASL YTNMNVFENY EASKAYSSVD EYFWGKPPST GDVFVIVFEN PIIIKKIKVN TGTEDRQNDI LHHGALDVGE NVMPSKQRRQ CSSYLRLGEF KNGNFEMSGV NQKIPFDIHC MRIYVTKTQK EWLIIRSISI WTS (127-478 aa encoded by BC064141)
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; GlcNAc-T IVc; GnT-IVc; hGnT-IV-H; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative); MGAT4 family, member C; N-acetylglucosaminyltransferase IV homolog; N-acetylglucosaminyltransferase IVc; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV; UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV-homolog
Gene Aliases: 9130411I17Rik; GNTIVH; HGNT-IV-H; MGAT4C; RGD1307871
UniProt ID: (Human) Q9UBM8, (Mouse) Q9D306
Entrez Gene ID: (Human) 25834, (Rat) 299756, (Mouse) 67569
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