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产品信息
10770-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MSI2 Fusion Protein Ag1213 (1-328 aa encoded by BC001526)
偶联物
Unconjugated
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MEANGSQGT SGSANDSQHD PGKMFIGGLS WQTSPDSLRD YFSKFGEIRE CMVMRDPTTK RSRGFGFVTF ADPASVDKVL GQPHHELDSK TIDPKVAFPR RAQPKMVTRT KKIFVGGLSA NTVVEDVKQY FEQFGKVEDA MLMFDKTTNR HRGFGFVTFE NEDVVEKVCE IHFHEINNKM VECKKAQPKE VMFPPGTRGR ARGLPYTMDA FMLGMGMLGY PNFVATYGRG YPGFAPSYGY QFPGFPAAAY GPVAAAAVAA ARGSGSNPAR PGGFPGANSP GPVADLYGPA SQDSGVGNYI SAASPQPGSG FGHGIAGPLI ATAFTNGYH (1-328 aa encoded by BC001526 )
靶标信息
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Musashi homolog 2; musashi RNA-binding protein 2; Musashi-2; Musashi2; RNA-binding protein Musashi homolog 2
基因别名: 1700105C15Rik; AI451722; AI563628; AW489193; MSI2; MSI2H; RGD1560397
UniProt ID: (Human) Q96DH6, (Mouse) Q920Q6
Entrez Gene ID: (Human) 124540, (Mouse) 76626, (Rat) 360596
