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Product Details
14547-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MSRA Fusion Protein Ag6053 (1-235 aa encoded by BC054033)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLSATRRAC QLLLLHSLFP VPRMGNSASN IVSPQEALPG RKEQTPVAAK HHVNGNRTVE PFPEGTQMAV FGMGCFWGAE RKFWVLKGVY STQVGFAGGY TSNPTYKEVC SEKTGHAEVV RVVYQPEHMS FEELLKVFWE NHDPTQGMRQ GNDHGTQYRS AIYPTSAKQM EAALSSKENY QKVLSEHGFG PITTDIREGQ TFYYAEDYHQ QYLSKNPNGY CGLGGTGVSC PVGIKK (1-235 aa encoded by B C054033)
Target Information
Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cytosolic methionine-S-sulfoxide reductase; Mitochondrial peptide methionine sulfoxide reductase; peptide met (O) reductase; Peptide Met(O) reductase; peptide methionine sulfoxide reductase; Peptide-methionine (S)-S-oxide reductase; PMSR; Protein-methionine-S-oxide reductase
Gene Aliases: 2310045J23Rik; 6530413P12Rik; MSR-A; MSRA; PMSR
UniProt ID: (Human) Q9UJ68, (Rat) Q923M1, (Mouse) Q9D6Y7
Entrez Gene ID: (Human) 4482, (Rat) 29447, (Mouse) 110265
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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