Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MSEPQPRGA ERDLYRDTWV RYLGYANEVG EAFRSLVPAA VVWLSYGVAS SYVLADAIDK GKKAGEVPSP EAGRSARVTV AVVDTFVWQA LASVAIPGFT INRVCAASLY VLGTATRWPL AVRKWTTTAL GLLTIPIIIH PIDRSVDFLL DSSLRKLYPT VGKPSSS (1-166 aa encoded by BC038831)
MTP18 (mitochondrial 18 kDa protein), also known as HSPC242, is a 166 amino acid protein essential for cell viability. MTP18 may also have a role in maintaining the integrity of the mitochondrial network. Localized to the mitochonrion, expression of MTP18 is regulated by the PI 3-kinase pathway. Loss of function of MTP18 results in the release of cytochrome c, which subsequently activates the caspase cascade and leads to apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Mitochondrial 18 kDa protein; Mitochondrial fission process protein 1; mitochondrial fission protein MTP18; mitochondrial protein 18 kDa; MTP18
Gene Aliases: 1700020C11Rik; 2610507A21Rik; AV005788; HSPC242; MTFP1; MTP18; My022
UniProt ID: (Human) Q9UDX5, (Mouse) Q9CRB8
Entrez Gene ID: (Human) 51537, (Mouse) 67900, (Rat) 289745
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