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Product Details
CL488-67351
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
2D9B7
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20° C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: RYSLTPEGLE LAQKLAESEG LSLLNVGIGP KEPPGEETAV PGAASAELAS EAGVQQQPLE LRPGEYRVLL CVDIGETRGG GHRPELLREL QRLHVTHTVR KLHVGDFVWV AQETNPRDPA NPGELVLDHI VERKRLDDLC SSIIDGRFRE QKFRLKRCGL ERRVYLVEEH GSVHNLSLPE STLLQAVTNT QVIDGFFVKR TADIKESAAY LALLTRGLQR LYQGHTLRSR PWGTPGNPES GAMTSPNPLC SLLTFSDFNA GAIKNKAQSV REVFARQLMQ VRGVSGEKAA ALVDRYSTPA SLLAAYDACA TPKEQETLLS TIKCGRLQRN LGPALSRTLS QLYCSYGPLT
Target Information
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Crossover junction endonuclease MUS81; FLJ21012; FLJ44872 MUS81; MUS81 endonuclease homolog; SLX3 structure-specific endonuclease subunit homolog
Gene Aliases: MUS81; SLX3
UniProt ID: (Human) Q96NY9
Entrez Gene ID: (Human) 80198
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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