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            • Primary Antibodies ›
            • MYH6 Antibodies

            Invitrogen

            MYH6 Polyclonal Antibody

            View all (12) MYH6 antibodies
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            Cite MYH6 Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            MYH6 Antibody in Western Blot (WB)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            MYH6 Antibody (PA5-116369) in WB

            Western Blot analysis of MYH6 using the MYH6 Polyclonal Antibody (Product # PA5-116369) at a 1:2000 dilution. Lane 1: human skeletal muscle lysate, Lane 2: mouse skeletal muscle lysate. Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10,000 dilution. Predicted band size : 224 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
            View Product

            MYH6 Antibody in Western Blot (WB)

            Product Details

            PA5-116369

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:2,000
            -
            Product Specifications

            Species Reactivity

            Human, Mouse

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            KLH conjugated synthetic peptide between 833-867 amino acids from the Central region of human MYH6
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.3 mg/mL

            Purification

            Protein A, Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.4

            Contains

            0.09% sodium azide

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2901003

            Target Information

            Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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            Cite this product

            Bioinformatics

            Protein Aliases: alpha cardiac MHC; alpha myosin; cardiac myosin heavy chain alpha isoform; cardiomyopathy, hypertrophic 1; MyHC-alpha; myosin 6; Myosin heavy chain 6; Myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha); myosin heavy chain, cardiac muscle, adult; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); Myosin-6

            View more View less

            Gene Aliases: A830009F23Rik; AA517445; alpha-MHC; ASD3; CMD1EE; CMH14; MYH6; MYHC; Myhc-a; MYHCA; SSS3

            View more View less

            UniProt ID: (Human) P13533, (Mouse) Q02566

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            Entrez Gene ID: (Human) 4624, (Mouse) 17888

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            Function(s)

            microfilament motor activity actin binding calmodulin binding ATP binding ATPase activity myosin phosphatase activity protein kinase binding actin-dependent ATPase activity nucleotide binding motor activity protein binding calcium-dependent ATPase activity identical protein binding protein homodimerization activity protein heterodimerization activity

            Process(es)

            in utero embryonic development regulation of the force of heart contraction regulation of heart rate muscle contraction striated muscle contraction adult heart development visceral muscle development regulation of heart contraction metabolic process regulation of blood pressure actin filament-based movement muscle filament sliding myofibril assembly BMP signaling pathway regulation of ATPase activity sarcomere organization ATP metabolic process cardiac muscle fiber development atrial cardiac muscle tissue morphogenesis ventricular cardiac muscle tissue morphogenesis cardiac muscle contraction canonical Wnt signaling pathway regulation of heart growth protein dephosphorylation
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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