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            • Primary Antibodies ›
            • MYL3 Antibodies

            Invitrogen

            MYL3 Polyclonal Antibody

            View all (17) MYL3 antibodies

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            Catalog # PA5-106802
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            Price (EUR)
            493,00
            100 µL
             
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            Cite MYL3 Polyclonal Antibody

            • Antibody Testing Data (5)
            Application
            MYL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 5

            MYL3 Antibody (PA5-106802) in IHC (P)

            Immunohistochemistry analysis of MYL3 in human pancreatic cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with MYL3 polyclonal antibody (Product # PA5-106802) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
            View Product

            MYL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            MYL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            MYL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            MYL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            MYL3 Antibody in Western Blot (WB)

            Product Details

            PA5-106802

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:1,000
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:50-1:200
            -

            Immunocytochemistry (ICC/IF)

            1:100-1:500
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            A synthesized peptide derived from human MYL3(Accession P08590), corresponding to amino acid residues D78-G128.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Affinity chromatography

            Storage buffer

            PBS, pH 7.4, with 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2854470

            Product Specific Information

            Antibody detects endogenous levels of total MYL3.

            Target Information

            MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: Cardiac myosin light chain 1; CMLC1; MLC-lV/sb; MLC1SB; MLClV; Myosin alkali light chain 1, ventricular; Myosin alkali light chain 1, ventricular/slow skeletal muscle isoform; Myosin light chain 1, slow-twitch muscle B/ventricular isoform; Myosin light chain 3; Myosin light chain 3, alkali, cardiac ventricles; myosin light chain, alkali, cardiac ventricles; myosin, light chain 3, alkali; ventricular, skeletal, slow; myosin, light polypeptide 3; myosin, light polypeptide 3, alkali; ventricular, skeletal, slow; rVMLC1; slow skeletal; ventricular; Ventricular myosin alkali light chain; Ventricular myosin light chain 1; ventricular, skeletal, slow; Ventricular/slow twitch myosin alkali light chain; VLCl

            View more View less

            Gene Aliases: CMH8; MLC-lV/sb; MLC1s; MLC1SB; MLC1V; MYL3; Mylc; Mylc1v; VLC1; VLCl

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            UniProt ID: (Human) P08590, (Mouse) P09542, (Rat) P16409

            View more View less

            Entrez Gene ID: (Human) 4634, (Mouse) 17897, (Rat) 24585

            View more View less

            Function(s)

            motor activity actin monomer binding calcium ion binding structural constituent of muscle myosin II heavy chain binding actin or actin-binding cytoskeletal protein

            Process(es)

            regulation of the force of heart contraction regulation of striated muscle contraction skeletal muscle tissue development muscle filament sliding positive regulation of ATPase activity ventricular cardiac muscle tissue morphogenesis cardiac muscle contraction metabolic process muscle contraction
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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