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            • Primary Antibodies ›
            • MYO15A Antibodies

            Invitrogen

            MYO15A Polyclonal Antibody

            View all (4) MYO15A antibodies
            Datasheet
            Protocols
            Questions & Answers
            Tech Support
            Catalog # PA5-144363
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            100 µL
             
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            Cite MYO15A Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            MYO15A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            MYO15A Antibody (PA5-144363) in IHC (P)

            Immunohistochemistry analysis with a MYO15A polyclonal antibody (Product # PA5-144363) using a dilution of 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 min at RT. Then primary antibody (1% BSA) was incu... View More
            View Product

            MYO15A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

            Product Details

            PA5-144363

            Applications
            Tested Dilution
            Publications

            Immunohistochemistry (Paraffin) (IHC (P))

            1:200-1:500
            -

            ELISA (ELISA)

            Assay-dependent
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant Human Unconventional myosin-XV protein (237-451AA)
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            3.27 mg/mL

            Purification

            Protein G

            Storage buffer

            PBS, pH 7.4, with 50% glycerol

            Contains

            0.03% Proclin 300

            Storage conditions

            -20°C or -80°C if preferred

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_3091531

            Target Information

            This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008].

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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            Cite this product

            Bioinformatics

            Protein Aliases: myosin-XV; Unconventional myosin-15; Unconventional myosin-XV

            View more View less

            Gene Aliases: DFNB3; MYO15; MYO15A

            View more View less

            UniProt ID: (Human) Q9UKN7

            View more View less

            Entrez Gene ID: (Human) 51168

            View more View less

            Function(s)

            motor activity actin binding calmodulin binding ATP binding actin binding motor protein

            Process(es)

            sensory perception of sound locomotory behavior inner ear morphogenesis
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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