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Immunogen sequence: MESALTARDR VGVQDFVLLE NFTSEAAFIE NLRRRFRENL IYTYIGPVLV SVNPYRDLQI YSRQHMERYR GVSFYEVPPH LFAVADTVYR ALRTERRDQA VMISGESGAG KTEATKRLLQ FYAETCPAPE RGGAVRDRLL QSNPVLEAFG NAKTLRNDNS SRFGKYMDVQ FDFKGAPVGG HILSYLLEKS RVVHQNHGER NFHIFYQLLE GGEEETLRRL GLERNPQSYL YLVKGQCAKV SSINDKSDWK VVRKALTVID FTEDEVEDLL SIVASVLHLG NIHFAANEES NAQVTTENQL KYLTRLLSVE GSTLREALTH RKIIAKGEEL LSPLNLEQAA YARDALAKAV
MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ23903; MMI-beta; MMIb; Myosin heavy chain myr 2; Myosin I beta; myosin IC-like; myosin-I beta; myosin-Ibeta; myosin-Ic; nuclear myosin I; nuclear myosin I beta; unconventional myosin Myr2 I heavy chain; Unconventional myosin-Ic
Gene Aliases: C80397; mm1beta; MMI-beta; MMIb; MYO1C; MYO1E; Myr2; NMI
UniProt ID: (Human) O00159, (Rat) Q63355, (Mouse) Q9WTI7
Entrez Gene ID: (Human) 4641, (Rat) 65261, (Mouse) 17913
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