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Invitrogen
MYOZ2 Polyclonal Antibody
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Application
FIGURE: 1 / 3
MYOZ2 Antibody (PA5-98905) in ICC/IF
Immunofluorescent analysis of MYOZ2 in Hela cells using a MYOZ2 polyclonal antibody (Product # PA5-98905) at a dilution of 1:100. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L). Cells were counter-stained with DAPI.
Product Details
PA5-98905
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Myozenin-2 protein (90-180AA)
Conjugate
Unconjugated
Form
Liquid
Concentration
4.31 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2813518
Target Information
The calcineurin-binding protein Myozenin 2, also designated calsarcin-1, is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase that is involved in controlling the slow fiber gene expression in skeletal muscle and hypertrophy of cardiac muscle. The calsarcins are sarcomeric proteins that couple calcineurin and muscle activity. In cardiac and skeletal muscle cells, Myozenin 2 binds calcineurin to α-actinin at the Z-line of the sarcomere. During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. The Myozenin 2 gene maps to chromosome 4q and is expressed specifically in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is only detected in fast skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcineurin-binding protein calsarcin-1; Calsarcin-1; FATZ-related protein 2; muscle-specific protein; MYOZ2; Myozenin-2
Gene Aliases: C4orf5; CMH16; CS-1; MYOZ2
UniProt ID: (Human) Q9NPC6
Entrez Gene ID: (Human) 51778
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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