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This antibody detects endogenous protein at a molecular weight of 256 kDa.
Purity is >95% by SDS-PAGE.
Neuron navigator 3 (NAV3), also known as pore membrane and/or filamentinteracting-like protein 1 (POMFIL1), unc-53 homolog 3 (unc53H3) or STEERIN3, is a 2,385 amino acid protein that localizes to the nuclear outer membrane and plays a role in neuron regeneration. Existing as three alternatively spliced isoforms, Neuron navigator 3 is highly expressed in adult and fetal brain and is found at moderate to low levels in ovary, lung, testis, placenta and heart. Neuron navigator 3 is thought be involved in the regulation of IL-2 production and contains one CH (calponin-homology) domain, three N-terminal hydrophobic domains, multiple N-glycosylation sites, three ATP/GTP-binding A motifs (P loops) and several phosphorylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Neuron navigator 3; pore membrane and/or filament interacting like protein 1; Pore membrane and/or filament-interacting-like protein 1; steerin 3; Steerin-3; Unc-53 homolog 3; unc53H3
Gene Aliases: 4732483H20Rik; 9630020C08Rik; KIAA0938; mKIAA0938; NAV3; POMFIL1; Pomfil1p; RGD1306259; STEERIN3; unc53H3
UniProt ID: (Human) Q8IVL0
Entrez Gene ID: (Human) 89795, (Rat) 314814, (Mouse) 260315
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