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This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp451M0318; endooligopeptidase A; Mitosin-associated protein 1; mitosin-associated protein MITAP1; Nuclear distribution protein nudE-like 1; nudE neurodevelopment protein 1-like 1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog-like 1; NUDE-like protein; Protein Nudel
Gene Aliases: EOPA; MITAP1; NDE1L1; NDE2; NDEL1; NUDEL
UniProt ID: (Human) Q9GZM8
Entrez Gene ID: (Human) 81565
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