Loading ...

Proteintech

NEURL Polyclonal Antibody

1 Reference

View all (4) NEURL1 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (4)

Application

FIGURE: 1 / 4

NEURL Antibody (18898-1-AP) in WB

Mouse brain tissue were subjected to SDS PAGE followed by western blot with 18898-1-AP (NEURL antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

NEURL Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

18898-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NEURL Fusion Protein Ag13531 (1-345 aa encoded by BC026336)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is specific to NEURL.

Immunogen sequence: MGNNFSSIP SLPRGNPSRA PRGHPQNLKD SIGGPFPVTS HRCHHKQKHC PAVLPSGGLP AAPLLFHPHT KGSQILMDLS HKAVKRQASF CNAITFSNRP VLIYEQVRLK ITKKQCCWSG ALRLGFTSKD PSRIHPDSLP KYACPDLVSQ SGFWAKALPE EFANEGNIIA FWVDKKGRVF HRINDSAVML FFSGVRTADP LWALVDVYGL TRGVQLLDSE LVLPDCLRPR SFTALRRPSL RREADDARLS VSLCDLNVPG ADGDEAAPAA SCPIPQNSLN SQHSRALPAQ LDGDLRFHAL RAGAHVRILD EQTVARVEHG RDERALVFTS RPVRVAETIF VKVTRS (1-345 aa encoded by B C026336)

Target Information

NEURL is involved in the determination of cell fate in the neurogenic region of the embryo and plays a role in the determination of cell fate in the central nervous system. NEURL may act as a tumor suppressor whose inactivation could be associated with malignant progression of astrocytic tumors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

CB1 agonism prolongs therapeutic window for hormone replacement in ovariectomized mice.

The Journal of clinical investigation

Zhang K,Yang Q,Yang L,Li YJ,Wang XS,Li YJ,Dang RL,Guan SY,Guo YY,Sun T,Wu YM,Liu A,Zhang Y,Liu SB,Zhao MG

Mon May 06 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: E3 ubiquitin-protein ligase NEURL1; h neu; h neuralized 1; h-neu; h-neuralized 1; neuralized homolog; neuralized homolog 1A; neuralized-like homolog; Neuralized-like protein 1A; RING finger protein 67; RING-type E3 ubiquitin transferase NEURL1

Gene Aliases: bA416N2.1; neu; neu-1; NEUR1; NEURL; NEURL1; NEURL1A; RNF67

UniProt ID: (Human) O76050

Entrez Gene ID: (Human) 9148, (Rat) 309459

Function(s)

ubiquitin-protein transferase activity zinc ion binding ligase activity translation factor activity, non-nucleic acid binding ubiquitin protein ligase activity molecular_function ubiquitin-protein ligase

Process(es)

regulation of translation protein monoubiquitination Notch signaling pathway sperm axoneme assembly nervous system development brain development skeletal muscle tissue development lactation negative regulation of cell proliferation sperm motility positive regulation of apoptotic process positive regulation of epidermal growth factor-activated receptor activity negative regulation of Notch signaling pathway positive regulation of long-term neuronal synaptic plasticity positive regulation of filopodium assembly positive regulation of dendritic spine development cellular response to amino acid stimulus positive regulation of synapse maturation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more