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Product Details
PA5-64917
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human NFIX. Recombinant protein control fragment (Product #RP-104554).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2663319
Product Specific Information
Immunogen sequence: SPSYYNINQVT LGRRSITSPP STSTTKRPKS IDDSEMESPV DDVFYPGTGR SPAAGSSQSS GWPNDVDAGS PRATASALHF PSTSIIQQSS PYFTHPTIRY HHHHGQDSLK EFVQFVCSDG SGQATGQHSQ RQAPPLPTGL SASD
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 78%.
Target Information
NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCAAT-binding transcription factor; CCAAT-box-binding transcription factor; CTF; KIAA1439; NF-I/X; NF1-X; NFI; NFI-A; NFI-B; NFI-C; NFIA; NFIB; NFIC; Nuclear factor 1 X-type; Nuclear factor 1/A; Nuclear factor 1/B; Nuclear factor 1/C; nuclear factor 1/X; Nuclear factor I/X; nuclear factor I/X (CCAAT-binding transcription factor); TGGCA-binding protein
Gene Aliases: MRSHSS; NF1A; NFIX; SOTOS2
UniProt ID: (Human) Q14938
Entrez Gene ID: (Human) 4784
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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