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Application
Product Details
75-108
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N49A/21
Immunogen
Fusion protein amino acids 551-640 of human NGL-1 (accession number NP_065980) produced recombinantly in E. Coli.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4
Contains
0.065% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
Leucine-rich repeat-containing 4C (LRRC4C), also known as Netrin-G ligand 2 (NGL-2), is a gene highlighted for its expression in the nervous system, particularly the brain. It is a member of the leucine-rich repeat superfamily, which plays a significant role in cell adhesion and signaling pathways critical for synaptic connectivity and neuronal development. LRRC4C is involved in neural processes such as axon guidance and synapse formation, aiding in the establishment of functional neural circuits. Additionally, research has suggested that LRRC4C may function as a tumor suppressor, particularly in gliomas, indicating its potential role in neuro-oncological disorders. Variations or deletions in this gene have been linked to neurodevelopmental disorders, demonstrating its importance in normal brain function and development. Furthermore, LRRC4C's expression patterns and associations with cancer also suggest its potential as a prognostic marker in clinical settings.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Leucine-rich repeat-containing protein 4C; Netrin-G1 ligand; NGL-1
Gene Aliases: 6430556C10Rik; KIAA1580; LRRC4C; NGL-1; NGL1; RGD1311013; UNQ292/PRO331
UniProt ID: (Human) Q9HCJ2, (Mouse) Q8C031
Entrez Gene ID: (Human) 57689, (Mouse) 241568, (Rat) 311236
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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