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The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM, Nov 2002].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bHLHa35; Class A basic helix-loop-helix protein 35; Helix-loop-helix protein 1; HELIX-LOOP-HELIX PROTEIN 1 (HEN1) (NSCL); HEN-1; Nescient helix loop helix 1; NSCL-1
Gene Aliases: BHLHA35; HEN1; NHLH1; NSCL; NSCL1; Tal2
UniProt ID: (Human) Q02575, (Mouse) Q02576
Entrez Gene ID: (Human) 4807, (Rat) 289230, (Mouse) 18071
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