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Product Details
H00126205-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NLRP8 (AAI53175.1, 1 a.a. approximately 1048 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSDVNPPSDT PIPFSSSSTH SSHIPPWTFS CYPGSPCENG VMLYMRNVSH EELQRFKQLL LTELSTGTMP ITWDQVETAS WAEVVHLLIE RFPGRRAWDV TSNIFAIMNC DKMCVVVRRE INAILPTLEP EDLNVGETQV NLEEGESGKI RRYKSNVMEK FFPIWDITTW PGNQRDFFYQ GVHRHEEYLP CLLLPKRPQG RQPKTVAIQG APGIGKTILA KKVMFEWARN KFYAHKRWCA FYFHCQEVNQ TTDQSFSELI EQKWPGSQDL VSKIMSKPDQ LLLLLDGFEE LTSTLIDRLE DLSEDWRQKL PGSVLLSSLL SKTMLPEATL LIMIRFTSWQ TCKPLLKCPS LVTLPGFNTM EKIKYFQMYF GHTEEGDQVL SFAMENTILF SMCRVPVVCW MVCSGLKQQM ERGNNLTQSC PNATSVFVRY ISSLFPTRAE NFSRKIHQAQ LEGLCHLAAD SMWHRKWVLG KEDLEEAKLD QTGVTAFLGM SILRRIAGEE DHYVFTLVTF QEFFAALFYV LCFPQRLKNF HVLSHVNIQR LIASPRGSKS YLSHMGLFLF GFLNEACASA VEQSFQCKVS FGNKRKLLKV IPLLHKCDPP SPGSGVPQLF YCLHEIREEA FVSQALNDYH KVVLRIGNNK EVQVSAFCLK RCQYLHEVEL TVTLNFMNVW KLSSSSHPGS EAPESNGLHR WWQDLCSVFA TNDKLEVLTM TNSVLGPPFL KALAAALRHP QCKLQKLLLR RVNSTMLNQD LIGVLTGNQH LRYLEIQHVE VESKAVKLLC RVLRSPRCRL QCLRLEDCLA TPRIWTDLGN NLQGNGHLKT LILRKNSLEN CGAYYLSVAQ LERLSIENCN LTQLTCESLA SCLRQSKMLT HLSLAENALK DEGAKHIWNA LPHLRCPLQR LVLRKCDLTF NCCQDMISAL CKNKTLKSLD LSFNSLKDDG VILLCEALKN PDCTLQILEL ENCLFTSICC QAMASMLRKN QHLRHLDLSK NAIGVYGILT LCEAFSSQKK REEVIFCIPA WTRITSFSPT PHPPDFTGKS DCLSQINP
Target Information
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NACHT, leucine rich repeat and PYD containing 8; NACHT, LRR and PYD containing protein 8; NACHT, LRR and PYD domains-containing protein 8; NLR family, pyrin domain containing 8; Nucleotide-binding oligomerization domain protein 16; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 8; PYRIN and NACHT-containing protein 4
Gene Aliases: CLR19.2; NALP8; NLRP8; NOD16; PAN4
UniProt ID: (Human) Q86W28
Entrez Gene ID: (Human) 126205
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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