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Proteintech
NMNAT1 Polyclonal Antibody
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Application
Product Details
11399-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NMNAT1 Fusion Protein Ag1944 (1-279 aa encoded by BC014943)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MENSEKTEV VLLACGSFNP ITNMHLRLFE LAKDYMNGTG RYTVVKGIIS PVGDAYKKKG LIPAYHRVIM AELATKNSKW VEVDTWESLQ KEWKETLKVL RHHQEKLEAS DCDHQQNSPT LERPGRKRKW TETQDSSQKK SLEPKTKAVP KVKLLCGADL LESFAVPNLW KSEDITQIVA NYGLICVTRA GNDAQKFIYE SDVLWKHRSN IHVVNEWIAN DISSTKIRRA LRRGQSIRYL VPDLVQEYIE KHNLYSSESE DRNAGVILAP LQRNTAEAKT (1-279 aa encoded by BC014943)
Target Information
The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: deamido-NAD(+) diphosphorylase; deamido-NAD(+) pyrophosphorylase; EC 2.7.7.1; EC 2.7.7.18; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; NaMN adenylyltransferase 1; nicotinamide mononucleotide adenylyl transferase; Nicotinamide mononucleotide adenylyltransferase 1; Nicotinamide-nucleotide adenylyltransferase 1; nicotinamide/nicotinate mononucleotide adenylyltransferase 1; Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1; Nicotinate-nucleotide adenylyltransferase 1; NMN adenylyltransferase 1; NMN/NaMN adenylyltransferase 1; NMNATPNAT1; PNAT-1; pyridine nucleotide adenylyltransferase 1
Gene Aliases: 2610529L11Rik; 5730441G13Rik; D4Cole1e; LCA9; NMNAT; NMNAT1; PNAT1
UniProt ID: (Human) Q9HAN9, (Mouse) Q9EPA7
Entrez Gene ID: (Human) 64802, (Pig) 102160928, (Mouse) 66454
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