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Immunogen sequence: EPLEEDEEGD DEFDDEAPEE LTFASAQAEA REEERRVRET VRRDKTLLKE KRKRREELFI EQKKRKL
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 85%.
NOL7 is encoded by this gene localizes to the nucleolus, where it maintains nucleolar structure and cell growth rates. The encoded protein also functions as a tumor suppressor and regulator of angiogenesis. The RB tumor suppressor gene recruits transcription factors to this gene and positively regulates its expression. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Nucleolar protein 7; nucleolar protein 7, 27kDa; Nucleolar protein of 27 kDa; polyglutamine binding protein 3; retinoic acid repressible protein; U3 small nucleolar RNA-associated protein NOL7; U3 snoRNA-associated protein NOL7
Gene Aliases: C6orf90; dJ223E5.2; NOL7; NOP27; PQBP3; RARG-1
UniProt ID: (Human) Q9UMY1
Entrez Gene ID: (Human) 51406
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