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Application
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NOMO2 Antibody (PA5-95819) in WB
Western blot analysis of NOMO2 in extracts of BxPC3 cells. Samples were incubated with NOMO2 Polyclonal antibody (Product # PA5-95819) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-95819
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 873-1222 of human NOMO2 (NP_0010040601)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.97 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2807621
Product Specific Information
Immunogen sequence: YALAGVSFEI KAEDDQPLPG VLLSLSGGLF RSNLLTQDNG ILTFSNLSPG QYYFKPMMKE FRFEPSSQMI EVQEGQNLKI TITGYRTAYS CYGTVSSLNG EPEQGVAMEA VGQNDCSIYG EDTVTDEEGK FRLRGLLPGC VYHVQLKAEG NDHIERALPH HRVIEVGNND IDDVNIIVFR QINQFDLSGN VITSSEYLPT LWVKLYKSEN LDNPIQTVSL GQSLFFHFPP LLRDGENYVV LLDSTLPRSQ YDYILPQVSF TAVGYHKHIT LIFNPTRKLP EQDIAQGSYI ALPLTLLVLL AGYNHDKLIP LLLQLTSRLQ GVGALGQAAS DNSGPEDAKR QAKKQKTRRT; Positive Samples: BxPC3; Cellular Location: Endoplasmic reticulum membrane, Single-pass membrane protein
Target Information
This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). Two transcripts encoding different isoforms have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BOS complex subunit NOMO2; Nodal modulator 2; pM5 protein 2; pM5 protein, centromeric copy
Gene Aliases: Nomo; NOMO2; PM5
UniProt ID: (Human) Q5JPE7
Entrez Gene ID: (Human) 283820
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