Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Proteintech
Promotions
View available promotion(s)
Promo Code: P5877545 Don't miss out: buy 3, only pay for 2 Extended to June 20: take advantage of our 3 for 2 promotion. Whether you are restocking essentials or trying something new, now is a great time to get more for your money!. Learn more
Promo Code: RPUZZ25 Stock up on essentials to piece your discovery together Until June 27, save up to $650 and get an exclusive lab-themed hidden-object puzzle. Learn more
Immunogen sequence: FVTPHPRRIT PKFKSLSQTS SYNASMADSP GEESFEDLTE ESKTLAWNNI TKLQLHEHYK IHKEAVTGIT VSRNGSSVFT TSQDSTLKMF SKESKMLQRS ISFSNMALSS CLLLPGDATV ITSSWDNNVY FYSIAFGRRQ DTLMGHDDAV SKICWHDNRL YSASWDSTVK VWSGVPAEMP GTKRHHFDLL AELEHDVSVD TISLNAASTL LVSGTKEGTV NIWDLTTATL MHQIPCHSGI VCDTAFSPDS RHVLSTGTDG CLNVIDVQTG MLISSMTSDE PQRCFVWDGN SVLSGSQSGE LLVWDLLGAK ISERIQGHTG AVTCIWMNEQ CSSIITGGED RQIIFWKLQY
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Factor associated with N-SMase activation; Factor associated with neutral sphingomyelinase activation; neutral sphingomyelinase (N-SMase) activation associated factor; Protein FAN
Gene Aliases: FAN; GRAMD5; NSMAF
UniProt ID: (Human) Q92636
Entrez Gene ID: (Human) 8439
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support