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            • Primary Antibodies ›
            • NSUN6 Antibodies

            Invitrogen

            NSUN6 Polyclonal Antibody

            View all (6) NSUN6 antibodies
            Datasheet
            Protocols
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            Catalog # PA5-21823
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            Price (EUR)
            520,00
            100 µL
             
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            Cite NSUN6 Polyclonal Antibody

            • Antibody Testing Data (2)
            Application
            NSUN6 Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 2

            NSUN6 Antibody (PA5-21823) in ICC/IF

            Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NSUN6 (Product # PA5-21823) antibody at 1:200 dilution.
            View Product

            NSUN6 Antibody in Immunocytochemistry (ICC/IF)
            NSUN6 Antibody in Western Blot (WB)

            Product Details

            PA5-21823

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:3,000
            -

            Immunocytochemistry (ICC/IF)

            1:100-1:1,000
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant protein encompassing a sequence within the center region of human NSUN6. The exact sequence is proprietary.

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.84 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            0.1M tris glycine, pH 7, with 10% glycerol

            Contains

            0.01% thimerosal

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_11153931

            Product Specific Information

            Recommended positive controls: 293T, HeLaS3, HepG2, Molt-4.

            Predicted reactivity: Mouse (82%), Rat (81%), Bovine (90%).

            Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

            Target Information

            NSun6 is an RNA methyltransferase that catalyzes the methylation at position cytosine C72 in some tRNAs. NSUN6 has been reported to localize to the cytoplasm and largely colocalize with Golgi apparatus and pericentriolar matrix, indicating that NSUN6 modifies tRNAs in a late step in their biogenesis. NSun6 may also play a major role in bone metastasis and could be a valuable therapeutic target for bone metastasis.

            ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: ARL5B antisense RNA 1; NOL1/NOP2/Sun and PUA domain-containing protein 1; NOL1/NOP2/Sun domain family member 6; NOL1/NOP2/Sun domain family, member 6; NOP2/Sun domain family, member 6; nucleolar protein (NOL1/NOP2/sun) and PUA domains 1; tRNA (cytosine(72)-C(5))-methyltransferase NSUN6

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            Gene Aliases: 4933414E04Rik; ARL5B-AS1; NOPD1; NSUN6

            View more View less

            UniProt ID: (Human) Q8TEA1

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            Entrez Gene ID: (Human) 221078

            View more View less

            Function(s)

            tRNA binding RNA methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity

            Process(es)

            RNA methylation tRNA methylation
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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