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Product Details
PA5-41311
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human NUCB2
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2608253
Product Specific Information
Peptide sequence: MMKEHERREY LKTLNEEKRK EEESKFEEMK KKHENHPKVN HPGSKDQLKE
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 93%; Yeast: 91%
Target Information
NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA-binding protein NEFA; Epididymis secretory protein Li 109; Gastric cancer antigen Zg4; nesfatin 1; nesfatin-1; Nucleobindin-2; Nucleobindin-2/Nesfatin-1; nucleobinding 2; prepronefastin; Prepronesfatin
Gene Aliases: AI607786; Calnuc; HEL-S-109; NEFA; Nesfatin-1; NUCB2
UniProt ID: (Human) P80303, (Mouse) P81117
Entrez Gene ID: (Human) 4925, (Mouse) 53322
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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