Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
11181-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NUDT6 Fusion Protein Ag1638 (1-316 aa encoded by BC009842)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MRQPLSWGR WRAMLARTYG PGPSAGYRWA SGAQGYVRNP PVGACDLQGE LDRFGGISVR LARLDALDRL DAAAFQKGLQ AAVQQWRSEG RTAVWLHIPI LQSRFIAPAA SLGFCFHHAE SDSSTLTLWL REGPSRLPGY ASHQVGVAGA VFDESTRKIL VVQDRNKLKN MWKFPGGLSE PEEDIGDTAV REVFEETGIK SEFRSVLSIR QQHTNPGAFG KSDMYIICRL KPYSFTINFC QEECLRCEWM DLNDLAKTEN TTPITSRVAR LLLYGYREGF DKIDLTVEEL PAVYTGLFYK LYHKELPENY KTMKGID (1-316 aa encoded by BC009842)
Target Information
NUDT6 (nudix (nucleoside diphosphate linked moiety X)-type motif 6), also known as Antisense basic fibroblast growth factor or GFG-1, is a member of the Nudix hydrolase family of pyrophosphatases. Nudix hydrolases contain a characteristic Nudix domain and are responsible for catalyzing the hydrolysis of nucleoside diphosphate derivatives. The gene encoding NUDT6 is a FGF-2 gene antisense transcript, and NUDT6 is believed to regulate FGF-2 expression. FGF-2 is a mutifunctional heparin-binding growth factor important to angiogenesis, neuroectoderm development and wound healing. NUDT6 is expressed as two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: anti-sense basic fibroblast growth factor B; Antisense basic fibroblast growth factor; Antisense basic fibroblast growth factor B; Nucleoside diphosphate-linked moiety X motif 6; nudix (nucleoside diphosphate linked moiety X)-type motif 6; Nudix motif 6; Protein GFG
Gene Aliases: ASFGF2; Asfgf2b; FGF-AS; FGF2AS; Gfg; GFG-1; GFG1; NUDT6
UniProt ID: (Human) P53370, (Rat) P70563, (Mouse) Q8CH40
Entrez Gene ID: (Human) 11162, (Rat) 207120, (Mouse) 229228
growth factor activity
hydrolase activity
thiamine-pyrophosphatase activity
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
UDP-2,3-diacylglucosamine hydrolase activity
bis(5'-nucleosyl)-tetraphosphatase activity
dATP pyrophosphohydrolase activity
pyrophosphatase activity
dihydroneopterin monophosphate phosphatase activity
dihydroneopterin triphosphate pyrophosphohydrolase activity
dITP diphosphatase activity
dTTP diphosphatase activity
XTP diphosphatase activity
ATP-dependent 5'-3' DNA helicase activity
phosphocholine hydrolase activity
nucleotide phosphatase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support