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Antibodies Inc
Neuregulin-CRD (Cysteine-Rich Domain/Type III) Monoclonal Antibody (N126B/31)
Application
FIGURE: 1 / 1
Neuregulin-CRD (Cysteine-Rich Domain/Type III) Antibody (75-226) in WB
Tissue and transfected cell immunoblot: extracts of rat brain membrane (RBM) and COS cells transiently transfected with Myc-tagged Neuregulin-CRD (NRG-CRD) or untagged Kv2.1 plasmid and probed with N126B/31 (left), 19E10 (middle) and K89/41 (right) TC supe.
Product Details
75-226
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
N126B/31
Immunogen
Fusion protein amino acids 1-75 (membrane-associated N-terminus) of human Neuregulin-1 (accession number Q96IB3) produced recombinantly in E. Coli.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4
Contains
0.065% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
Neuregulin-CRD refers to the cysteine-rich domain (CRD) of neuregulins, a family of signaling proteins involved in various cellular processes, including growth, differentiation, and development. The cysteine-rich domain is critical for the interaction of neuregulins with their receptors, such as the ErbB family of receptor tyrosine kinases, facilitating the activation of downstream signaling pathways. This domain plays a vital role in the proper functioning of neuregulins in the nervous system, heart, and other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor-inducing activity; glial growth factor 2; heregulin, alpha (45kD, ERBB2 p185-activator); neu differentiation factor; neuregulin 1 type III beta 3; Pro-neuregulin-1, membrane-bound isoform; Pro-NRG1; sensory and motor neuron derived factor
Gene Aliases: ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; NRG1; NRG1-IT2; SMDF
UniProt ID: (Human) Q02297
Entrez Gene ID: (Human) 3084, (Rat) 112400
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