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Proteintech

Neurotrophin 3 Polyclonal Antibody

10 篇参考文献

查看其他18个NTF3抗体

问题与答案

问题与答案

抗体检测数据 (6)

Application

Neurotrophin 3 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 6

Neurotrophin 3 Antibody (18084-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed SH-SY5Y cells using 18084-1-AP (Neurotrophin 3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

Neurotrophin 3 Antibody in Immunocytochemistry (ICC/IF)

Neurotrophin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Neurotrophin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Neurotrophin 3 Antibody in Western Blot (WB)

Neurotrophin 3 Antibody in Western Blot (WB)

Neurotrophin 3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Neurotrophin 3 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( -20°C Ethanol ) fixed SH-SY5Y cells using 18084-1-AP (Neurotrophin 3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

Neurotrophin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human brain using 18084-1-AP (Neurotrophin 3 antibody) at dilution of 1:100 (under 40x lens).

Neurotrophin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human brain using 18084-1-AP (Neurotrophin 3 antibody) at dilution of 1:100 (under 10x lens).

Neurotrophin 3 Antibody in Western Blot (WB) — Human placenta tissue were subjected to SDS PAGE followed by western blot with 18084-1-AP (Neurotrophin 3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Neurotrophin 3 Antibody in Western Blot (WB) — SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 18084-1-AP (Neurotrophin 3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Neurotrophin 3 Antibody in Immunoprecipitation (IP) — IP result of anti-Neurotrophin 3 (IP: 18084-1-AP, 4 µg; Detection: 18084-1-AP 1:800) with SH-SY5Y cells lysate 1600 µg.

产品信息

18084-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:4,000

查看6篇已发表文章 6篇已发表文章

免疫组化 (IHC)

-

查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

1:20-1:200

-

免疫细胞化学 (ICC/IF)

1:20-1:200

查看1篇已发表文章 1篇已发表文章

免疫沉淀 (IP)

0.5-4.0 µg

-

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Neurotrophin 3 Fusion Protein Ag12798 (1-257 aa encoded by BC069773)

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.22 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MSILFYVIF LAYLRGIQGN NMDQRSLPED SLNSLIIKLI QADILKNKLS KQMVDVKENY QSTLPKAEAP REPERGGPAK SAFQPVIAMD TELLRQQRRY NSPRVLLSDS TPLEPPPLYL MEDYVGSPVV ANRTSRRKRY AEHKSHRGEY SVCDSESLWV TDKSSAIDIR GHQVTVLGEI KTGNSPVKQY FYETRCKEAR PVKNGCRGID DKHWNSQCKT SQTYVRALTS ENNKLVGWRW IRIDTSCVCA LSRKIGRT (1-257 aa encoded by BC069773)

靶标信息

The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: HDNF; Nerve growth factor 2; Neurotrophic factor; Neurotrophin-3; neurotrophin-3 (HDNF/NT-3); NGF-2; NT-3

基因别名: AI316846; AI835689; HDNF; NGF-2; NGF2; NT-3; NT3; Ntf-3; NTF3

UniProt ID: (Human) P20783, (Mouse) P20181, (Rat) P18280

Entrez Gene ID: (Human) 4908, (Mouse) 18205, (Rat) 81737

功能

receptor binding neurotrophin p75 receptor binding protein binding growth factor activity chemoattractant activity nerve growth factor binding neurotrophin receptor binding neurotrophic factor

参与通路

activation of MAPK activity positive regulation of receptor internalization signal transduction transmembrane receptor protein tyrosine kinase signaling pathway cell-cell signaling nervous system development positive regulation of cell proliferation positive regulation of cell migration activation of protein kinase B activity positive regulation of peptidyl-serine phosphorylation myelination regulation of apoptotic process negative regulation of neuron apoptotic process regulation of neuron differentiation positive regulation of glial cell differentiation neuron projection morphogenesis positive regulation of peptidyl-tyrosine phosphorylation negative regulation of peptidyl-tyrosine phosphorylation modulation of synaptic transmission positive chemotaxis induction of positive chemotaxis activation of GTPase activity positive regulation of actin cytoskeleton reorganization neuromuscular synaptic transmission glial cell fate determination axon guidance brain development peripheral nervous system development epidermis development nerve development mechanoreceptor differentiation regulation of neuron apoptotic process positive regulation of transcription from RNA polymerase II promoter enteric nervous system development neuron development generation of neurons smooth muscle cell differentiation

1x1 image pixel for data collection