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Invitrogen
Nogo Receptor Recombinant Rabbit Monoclonal Antibody (M5)
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Product Details
MA5-47935
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
M5
Immunogen
(His)6-tagged fragment of rat NgR1 (amino acids 278-473).
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.02% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3074379
Product Specific Information
Specificity: The antibody binds to human and rat NgR1 with a Kd of 2.9 nM for both species (bivalent binding).
Target Information
NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HGNC:1860; NgR; NgR1; nogo 66 receptor; Nogo receptor; nogo receptor; Nogo-66 receptor; Nogo-66 receptor; Nogo66 receptor; Nogo66 receptor-1; OTTHUMP00000197866; Reticulon-4 receptor; UNQ330/PRO526
Gene Aliases: NGR; NgR1; NOGOR; RTN4R; UNQ330/PRO526
UniProt ID: (Human) Q9BZR6, (Rat) Q99M75, (Mouse) Q99PI8
Entrez Gene ID: (Human) 65078, (Rat) 113912, (Mouse) 65079
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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