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Nudel Antibody (MA5-55621) in WB
Western blot analysis of Nudel in 15 µg of rat brain. Sample was run on 6-18% SDS-PAGE under reducing conditions, blotted onto nitrocellulose membrane, and peroxidase conjugated goat anti-mouse IgG was used as the secondary antibody. Nudel band was visualized using ECL Western Blotting Substrate. Incubation with primary Nudel monoclonal antibody (Product # MA5-55621) at a dilution of 1 µg/mL was used.
Product Details
MA5-55621
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
K52041_9G9
Immunogen
Recombinant human NDEL1 (immunogen range is 11-220).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Specific Information
Sequence of this protein is as follows: SLKEETAYWK ELSLKYKQSF QEARDELVEF QEGSRELEAE LEAQLVQAEQ RNRDLQADNQ RLKYEVEALK EKLEHQYAQS YKQVSVLEDD LSQTRAIKEQ LHKYVRELEQ ANDDLERAKR ATIVSLEDFE QRLNQAIERN AFLESELDEK ESLLVSVQRL KDEARDLRQE LAVRERQQEV TRKSAPSSPT LDCEKMDSAV QASLSLPATP
Target Information
This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp451M0318; endooligopeptidase A; LIS1-interacting protein NUDEL; LIS1-interacting protein NUDEL; endooligopeptidase A; Mitosin-associated protein 1; mitosin-associated protein MITAP1; mNudE-L; nuclear disribution gene E like; nuclear distribution gene E-like homolog 1; Nuclear distribution protein nudE-like 1; nudE neurodevelopment protein 1-like 1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog like 1; nudE nuclear distribution gene E homolog-like 1; NUDE-like protein; Protein mNudE-like; Protein Nudel
Gene Aliases: 2600006O07Rik; EOPA; MITAP1; mNudel; NDE1L1; NDE2; NDEL1; NUDE2; NUDEL
UniProt ID: (Human) Q9GZM8, (Rat) Q78PB6, (Mouse) Q9ERR1
Entrez Gene ID: (Human) 81565, (Rat) 170845, (Mouse) 83431
establishment of mitotic spindle orientation
microtubule cytoskeleton organization
neuron migration
inner cell mass cell proliferation
proteolysis
microtubule nucleation
chromosome segregation
mitotic centrosome separation
retrograde axonal transport
regulation of neuron projection development
cell migration
cerebral cortex radially oriented cell migration
central nervous system neuron axonogenesis
neuron projection development
positive regulation of axon extension
vesicle transport along microtubule
positive regulation of axon regeneration
nuclear envelope disassembly
establishment of chromosome localization
centrosome localization
neurofilament cytoskeleton organization
canonical Wnt signaling pathway
neuron projection extension
sister chromatid cohesion
regulation of intracellular protein transport
positive regulation of GTPase activity
activation of GTPase activity
regulation of microtubule motor activity
transport
multicellular organism development
nervous system development
cell differentiation
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