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Invitrogen
OLFM1 Polyclonal Antibody
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Application
FIGURE: 1 / 2
OLFM1 Antibody (PA5-102310) in IHC (P)
Immunohistochemistry analysis of OLFM1 in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with OLFM1 polyclonal antibody (Product # PA5-102310) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-102310
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human OLFM1(Accession Q99784), corresponding to amino acid residues F312-S362.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2851719
Product Specific Information
Antibody detects endogenous levels of total OLFM1.
Target Information
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1B426B; neuroblastoma protein; Neuronal olfactomedin-related ER localized protein; Noelin; Noelin 1; Noelin 2; olfactomedin related ER localized protein; Olfactomedin-1; Pancortin; pancortin 1; Pancortin 1-4
Gene Aliases: AMY; AW742568; D2Sut1e; NOE1; Noel; NOEL1; NOELIN1; OlfA; OLFM1; Pancortin; Pancortin3
UniProt ID: (Human) Q99784, (Mouse) O88998, (Rat) Q62609
Entrez Gene ID: (Human) 10439, (Mouse) 56177, (Rat) 93667
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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